Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MYOC | Q99972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742626 | 0.92 | ALDH1A1 (0.53) | HSPB1MAPTNPSR1RAB9AKMT2A | |
| SCHEMBL9742990 | 0.92 | ACHE (0.53) | HSPB1MAPTNPSR1RAB9AKMT2A | |
| SCHEMBL9742817 | 0.89 | SRD5A2 (0.68) | HSPB1MAPTNPSR1RAB9AKMT2A | |
| SCHEMBL9740641 | 0.87 | MAPT (0.49) | HSPB1MAPTNPSR1RAB9AKMT2A | |
| SCHEMBL9742737 | 0.87 | ALDH1A1 (0.58) | HSPB1MAPTNPSR1RAB9AKMT2A | |
| SCHEMBL4373201 | 0.86 | HSPB1 (0.65) | HSPB1MAPTNPSR1RAB9AKMT2A | |
| SCHEMBL9157220 | 0.85 | ALDH1A1 (0.51) | HSPB1MAPTNPSR1KMT2AMEN1 | |
| SCHEMBL27706701 | 0.82 | HSPB1 (0.60) | HSPB1MAPTNPSR1KMT2AMEN1 | |
| SCHEMBL27706167 | 0.82 | HSPB1 (0.68) | HSPB1MAPTNPSR1KMT2AMEN1 | |
| SCHEMBL7938396 | 0.82 | HSPB1 (0.55) | HSPB1MAPTRAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341348-A | Synthesis process of 2-bis [4- (4-aminophenoxy) phenyl ] hexafluoropropane | 兰州华浩生物医药科技有限责任公司 | 2021-02-09 | — | — | CN | claimed |
| US-5043478-A | Process for the preparation of fluorinate aromatic diamine | ETHYL CORPORATION (US) | 1991-08-27 | — | — | US | claimed |
| EP-0396926-A2 | Improved process for the preparation of fluorinated aromatic diamine | ETHYL CORPORATION (US) | 1990-11-14 | — | — | EP | claimed |
| JP-2304048-A | — | — | None | — | — | JP | disclosed |
| CN-116813486-A | Preparation method of 2, 2-bis [4- (4-aminophenoxy) phenyl ] propane | 天津众泰材料科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-112341348-A | Synthesis process of 2-bis [4- (4-aminophenoxy) phenyl ] hexafluoropropane | 兰州华浩生物医药科技有限责任公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112341348-A | Synthesis process of 2-bis [4- (4-aminophenoxy) phenyl ] hexafluoropropane | 兰州华浩生物医药科技有限责任公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-105001092-B | Method for preparing 2,2-di(4-(4-aminophenoxy)phenyl)hexafluoropropane and intermediate body thereof at low temperature | 广西科技大学 | 2017-01-11 | — | — | CN | disclosed |
| CN-105152937-A | Method for low temperature rapid preparation of 2, 2-bis(4-(4-aminophenoxy)phenyl)hexafluoropropane and intermediate thereof | UNIV GUANGXI SCI & TECHNOLOGY | 2015-12-16 | — | — | CN | disclosed |
| CN-105037166-A | Preparation method for 2,2-bis(4-(4-aminophenoxyl)phenyl)hexafluoropropane and intermediate thereof | UNIV GUANGXI SCI & TECHNOLOGY | 2015-11-11 | — | — | CN | disclosed |
| CN-105001092-A | Method for preparing 2,2-di(4-(4-aminophenoxy)phenyl)hexafluoropropane and intermediate body thereof at low temperature | UNIV GUANGXI SCI & TECHNOLOGY | 2015-10-28 | — | — | CN | disclosed |
| US-5130481-A | BIS-N,N' NITRO OR AMINO BENZOYL AMINO PHENOLS | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| US-5043478-A | Process for the preparation of fluorinate aromatic diamine | ETHYL CORPORATION (US) | 1991-08-27 | — | — | US | disclosed |
| JP-H02304048-A | IMPROVED PROCESS FOR PRODUCING FLUORINATED AROMATIC DIAMINE | ETHYL CORP | 1990-12-17 | — | — | JP | disclosed |
| EP-0396926-A2 | Improved process for the preparation of fluorinated aromatic diamine | ETHYL CORPORATION (US) | 1990-11-14 | — | — | EP | disclosed |
| EP-0387060-A2 | Bis-N,N' nitro or amino benzoyl aminophenols | HOECHST CELANESE CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4203922-A | Fluorinated aromatic diamine | TRW INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4203922-A | Fluorinated aromatic diamine | TRW INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4111906-A | POLYIMIDES PREPARED FROM PERFLUOROISOPROPYLIDENE DIAMINE | TRW INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4111906-A | POLYIMIDES PREPARED FROM PERFLUOROISOPROPYLIDENE DIAMINE | TRW INC. (US) | 1978-09-05 | — | — | US | disclosed |