Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MYOC | Q99972 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439543 | 0.88 | CA1 (0.60) | MAPTNPSR1RAB9AALDH1A1CA1 | |
| Dinitrophenylene SCHEMBL27323145 | 0.86 | LMNA (0.55) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| SCHEMBL9719384 | 0.86 | HSPB1 (0.61) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| SCHEMBL8109093 | 0.85 | MEN1 (0.78) | MAPTNPSR1RAB9AMEN1KMT2A | |
| SCHEMBL14678190 | 0.85 | MAPT (0.51) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.84 | HSPB1 (0.79) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| SCHEMBL11689190 | 0.84 | HSPB1 (0.79) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| SCHEMBL9183872 | 0.84 | HSPB1 (0.79) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| SCHEMBL2011179 | 0.84 | HSPB1 (0.79) | HSPB1MAPTNPSR1RAB9AMEN1 | |
| SCHEMBL30334516 | 0.84 | ALDH1A1 (0.54) | HSPB1MAPTNPSR1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626865-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| CN-118852135-A | N-acyl sulfonamide compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024118810-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| US-5290756-A | Herbicides | ROHM AND HAAS COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| US-5290756-A | Herbicides | ROHM AND HAAS COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| US-4913729-A | POSTEMERGENCE OR PREEMERGENCE | ROHM AND HAAS COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4877897-A | HERBICIDES | ROHM AND HAAS COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| US-4877897-A | HERBICIDES | ROHM AND HAAS COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0161529-B1 | 2-NITRO-5-(2'-CHLORO-4'TRIFLUOROMETHYLPHENOXY)PHENYLACETIC ESTER, THIOESTER AND AMIDE, PROCESS FOR PREPARATION THEROF, HERBICIDAL COMPOSITION, AND METHOD FOR DESTRUCTION OF UNDESIRABLE WEEDS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-07-12 | — | — | EP | disclosed |
| US-4468247-A | Herbicidal 4-[3'-(4\"-trifluoromethyl-phenoxy)-phenoxy]-4-methyl-crotonates | CHEVRON RESEARCH COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| US-4414017-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0084128-A1 | Process for the preparation of alkylbenzenes substituted by radicals containing fluorine | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
| US-4350522-A | Herbicidal 4-trifluoromethyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4185995-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| US-4104313-A | BERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4104313-A | BERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4104313-A | BERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4063929-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4046798-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-09-06 | — | — | US | disclosed |