Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320818 | 0.78 | RIPK1 (0.50) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL9719460 | 0.77 | SLC6A4 (0.42) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL9722972 | 0.75 | LTA4H (0.45) | ALDH1A1MAPK1HTTLTA4HTSHR | |
| SCHEMBL278540 | 0.74 | RIPK1 (0.53) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL8776759 | 0.74 | RIPK1 (0.53) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL9248440 | 0.72 | RIPK1 (0.52) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL3034914 | 0.71 | SLC6A4 (0.49) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL4350378 | 0.71 | ALDH1A1 (0.47) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL548378 | 0.71 | RIPK1 (0.50) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 | |
| SCHEMBL11176072 | 0.70 | DPP4 (0.47) | RIPK1HRH1CTNNB1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081196-A | Containing an acetylenically unsaturated monoamine compound | UBE INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | claimed |
| EP-0357367-A2 | Terminal-modified aromatic imide oligomer composition | UBE INDUSTRIES, LTD. (JP) | 1990-03-07 | — | — | EP | claimed |
| US-5147943-A | Thermosetting resin; polyimide containing a modifying monoamine alcohol | UBE INDUSTRIES, LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| US-5081196-A | Containing an acetylenically unsaturated monoamine compound | UBE INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0379131-A2 | Thermosetting resin composition | UBE INDUSTRIES, LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0357367-A2 | Terminal-modified aromatic imide oligomer composition | UBE INDUSTRIES, LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |