Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TARS1 | P26639 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114847 | 0.82 | KCNN4 (0.48) | MAOAMAPK1 | |
| SCHEMBL635988 | 0.79 | SLC6A4 (0.47) | MAOATSHRALDH1A1MAPK1CA1 | |
| SCHEMBL14596128 | 0.79 | SLC6A4 (0.47) | MAOATSHRALDH1A1MAPK1CA1 | |
| SCHEMBL22158987 | 0.76 | LTA4H (0.52) | LTA4HMAOATSHRNR1H2BAX | |
| SCHEMBL9719461 | 0.75 | RIPK1 (0.41) | LTA4HTSHRACACBALDH1A1MAPK1 | |
| SCHEMBL7598855 | 0.72 | LTA4H (0.52) | LTA4HMAOATSHRACACBNR1H2 | |
| SCHEMBL1744599 | 0.72 | LTA4H (0.52) | LTA4HMAOATSHRACACBNR1H2 | |
| SCHEMBL20558768 | 0.72 | LTA4H (0.52) | LTA4HMAOATSHRNR1H2BAX | |
| SCHEMBL9487460 | 0.72 | LTA4H (0.52) | LTA4HMAOATSHRACACBNR1H2 | |
| SCHEMBL506349 | 0.72 | LTA4H (0.52) | LTA4HMAOATSHRACACBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081196-A | Containing an acetylenically unsaturated monoamine compound | UBE INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0357367-A2 | Terminal-modified aromatic imide oligomer composition | UBE INDUSTRIES, LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |