SCHEMBL9719583

SCHEMBL9719583

BrC(Br)(OC(Br)(Br)C(Br)(Br)c1ccccc1)C(Br)(Br)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.37
KIF11 P52732 1/20 0.33
CYP1A2 P05177 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTPN1 P18031 1/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
ESR2 Q92731 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21647231 0.78 ALDH1A1 (0.50) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL10613777 0.76 ALDH1A1 (0.41) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL756427 0.73 KCNN4 (0.46) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL11658410 0.71 MAPK1 (0.43) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL11494643 0.70 MAPK1 (0.34) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL11660433 0.69 KCNN4 (0.48) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL9321087 0.69 KCNN4 (0.48) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL127092 0.67 ALDH1A1 (0.61) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL8973 0.67 KIF11 (0.48) KCNN4MAPK1ALDH1A1TSHRALOX15
SCHEMBL180622 0.65 ALDH1A1 (0.50) KCNN4MAPK1ALDH1A1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0247861-B1 FLAME RETARDANT POLYMER COMPOSITIONS Bromine Compounds Ltd. (IL) 1992-08-12 EP disclosed
EP-0247861-A2 Flame retardant polymer compositions Bromine Compounds Ltd. (IL) 1987-12-02 EP disclosed