SCHEMBL11494643

SCHEMBL11494643

BrC(Br)C(Br)(c1ccccc1)C(Br)(Br)OC(Br)(Br)C(Br)(c1ccccc1)C(Br)Br

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
KCNN4 O15554 3/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9719583 0.70 KCNN4 (0.40) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL4944350 0.70 KCNN4 (0.32) KCNN4TSHRALDH1A1
SCHEMBL651122 0.69 ALDH1A1 (0.43) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL10613777 0.69 ALDH1A1 (0.41) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL10590017 0.67 ALDH1A1 (0.41) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL11658410 0.64 MAPK1 (0.43) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL4531851 0.64 CES2 (0.37) TSHR
SCHEMBL4531858 0.64 MAPK1 (0.34) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL28818191 0.64 MAPK1 (0.44) MAPK1KCNN4TSHRALDH1A1ALOX15
SCHEMBL2860719 0.64 CYP1A2 (0.39) MAPK1KCNN4TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4182706-A Flame-retardant agents for phenolic resins and process for their production CHEMISCHE FABRIK KALK GMBH (DE) 1980-01-08 US disclosed
US-4056656-A PHENOLIC RESIN, PENTABROMODIPHENYL ETHER, PLASTICIZER DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed