Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20349586 | 0.85 | ALDH1A1 (0.47) | NPC1RAB9AHPGDMAPTPPARG | |
| SCHEMBL2910521 | 0.83 | PIN1 (0.54) | POLBMEN1KMT2AMAPTPIN1 | |
| SCHEMBL11160629 | 0.83 | NPC1 (0.46) | NPC1RAB9APOLBCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL28042251 | 0.83 | NPC1 (0.45) | NPC1RAB9APOLBCYP2C9HPGD | |
| SCHEMBL9719786 | 0.82 | AKR1C3 (0.51) | NPC1RAB9APOLBCYP2C9PTGS2 | |
| SCHEMBL16746822 | 0.80 | ACHE (0.45) | MAPTPIN1MMP8PPARGPPARA | |
| SCHEMBL20346302 | 0.80 | LMNA (0.47) | NPC1RAB9ACYP2C9HPGDMEN1 | |
| SCHEMBL11502244 | 0.78 | HTT (0.45) | NPC1RAB9APOLBCYP2C9HPGD | |
| SCHEMBL11172538 | 0.78 | PPARA (0.51) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL8469055 | 0.78 | GAA (0.50) | NPC1RAB9AHPGDPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078906-A | Organic lithium-potassium complexes for metallization reactions, preparation of aspirin substitutes, fenoprofen | MINE SAFETY APPLIANCES COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| US-4910337-A | Process for the preparation of α-arylalkanoic acids | MINE SAFETY APPLIANCES COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| US-4393008-A | 2-Cyano-2-(3-phenoxy-phenyl)-propionic acid amide and preparation thereof | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1983-07-12 | — | — | US | disclosed |
| US-4308208-A | α-Methylthio-α-(p-phthalimidophenyl)-propionic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4304930-A | Process for the preparation of 2-(3-phenoxy-phenyl)-propionic acid | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1981-12-08 | — | — | US | disclosed |
| US-4278802-A | METHYLTHIO-/P-/2-THIENYLCARBONYL/PHENYL/PROPIONIC ACID OR ESTER, PHARMACEUTICAL INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-07-14 | — | — | US | disclosed |
| US-4242519-A | DRUG INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4237298-A | Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4144248-A | Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1979-03-13 | — | — | US | disclosed |