Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849156 | 0.87 | GABRA1 (0.67) | GABRA1GABRB2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL327806 | 0.83 | SLC6A4 (0.63) | SLC6A4SLC6A2RIPK1HRH1SLC6A3 | |
| SCHEMBL29060668 | 0.81 | PPARA (0.48) | SLC6A4SLC6A2RIPK1HRH1LTA4H | |
| SCHEMBL11128502 | 0.81 | PPARA (0.48) | SLC6A4SLC6A2RIPK1HRH1LTA4H | |
| Hydrogen Sulfide SCHEMBL28150140 | 0.81 | SLC6A4 (0.61) | SLC6A4SLC6A2RIPK1HRH1SLC6A3 | |
| SCHEMBL9780467 | 0.80 | LTA4H (0.52) | SLC6A4SLC6A2RIPK1HRH1SLC6A3 | |
| SCHEMBL22185409 | 0.79 | SLC6A4 (0.50) | SLC6A4SLC6A2RIPK1HRH1SLC6A3 | |
| SCHEMBL28156480 | 0.79 | HRH1 (0.51) | SLC6A4SLC6A2RIPK1HRH1SLC6A3 | |
| SCHEMBL12806081 | 0.77 | GABRA1 (0.64) | GABRA1GABRB2KMT2AL3MBTL1ATM | |
| SCHEMBL31200741 | 0.77 | GABRA1 (0.64) | GABRA1GABRB2KMT2AL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078906-A | Organic lithium-potassium complexes for metallization reactions, preparation of aspirin substitutes, fenoprofen | MINE SAFETY APPLIANCES COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0379987-A2 | Process for the preparation of alpha-arylalkanoic acids | Mine Safety Appliances Company (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4910337-A | Process for the preparation of α-arylalkanoic acids | MINE SAFETY APPLIANCES COMPANY (US) | 1990-03-20 | — | — | US | disclosed |