Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687729 | 0.84 | HRH1 (0.58) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| SCHEMBL327806 | 0.83 | SLC6A4 (0.63) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| SCHEMBL11387994 | 0.82 | HRH1 (0.47) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| Hydrochloric Acid SCHEMBL921538 | 0.82 | HRH1 (0.56) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| SCHEMBL27854361 | 0.81 | CXCL8 (0.58) | HRH1GAA | |
| Hydrogen Sulfide SCHEMBL28150140 | 0.81 | SLC6A4 (0.61) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| SCHEMBL8621202 | 0.80 | HRH1 (0.43) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| SCHEMBL9719836 | 0.79 | GABRA1 (0.55) | SLC6A4SLC6A2RIPK1HRH1HTR2A | |
| SCHEMBL28156480 | 0.79 | HRH1 (0.51) | SLC6A4SLC6A2RIPK1HRH1LMNA | |
| SCHEMBL18313564 | 0.78 | AR (0.51) | SLC6A4SLC6A2RIPK1HRH1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | IDH1, IDH2, IDH3A | SLC6A4 4679/4885SLC6A2 4593/4885RIPK1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.