Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462777 | 0.76 | F7 (0.36) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11468990 | 0.76 | PIK3CG (0.47) | NPC1RAB9AALDH1A1METAP2METAP1 | |
| SCHEMBL782083 | 0.73 | ALDH1A1 (0.37) | ALDH1A1NR4A2HPGDSMN1; SMN2F7 | |
| SCHEMBL781743 | 0.70 | PIK3CG (0.47) | NPC1RAB9AALDH1A1NR4A2HPGD | |
| SCHEMBL781974 | 0.70 | AMY1A (0.38) | ALDH1A1HPGDSMN1; SMN2F7F3 | |
| SCHEMBL5081902 | 0.68 | HTR3A (0.45) | NPC1RAB9AALDH1A1NR4A2CYP3A4 | |
| SCHEMBL11602714 | 0.68 | MAT2A (0.46) | RAB9AALDH1A1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL11601709 | 0.68 | TSHR (0.41) | ALDH1A1HPGDMAPTKDM4EKMT2A | |
| SCHEMBL11602976 | 0.68 | HPGD (0.38) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11464996 | 0.67 | GAA (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086048-A | 1,2,4-triazole of phenoxyether-ketones and phenoxyether-alkanols and copper complexes | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4990528-A | Mixture of fungicidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4888349-A | 1,2,4-TRIAZOLE DERIVATIVES OF PHENOXYKETONES OR ALKANOLS MIXED WITH IMIDAZOLE DERIVATIVES OF PHENYL SUBSTITUTED UNSATURATED ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-19 | — | — | US | disclosed |
| US-4514402-A | 1,2,4-TRIAZOLE AND QUINOXALINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-30 | — | — | US | disclosed |