Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 7/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716332 | 0.91 | — | — | |
| SCHEMBL9716400 | 0.89 | — | — | |
| SCHEMBL9720221 | 0.85 | PLA2G2A (0.38) | — | |
| SCHEMBL9720263 | 0.85 | PLA2G2A (0.38) | — | |
| SCHEMBL9720171 | 0.84 | NAAA (0.33) | NAAAPTGESHPGD | |
| SCHEMBL9720198 | 0.80 | PLA2G2A (0.39) | HPGD | |
| SCHEMBL9716384 | 0.76 | PLA2G2C (0.33) | — | |
| SCHEMBL9716406 | 0.76 | TLR2 (0.33) | — | |
| SCHEMBL10549500 | 0.74 | MAPK14 (0.38) | NAAA | |
| SCHEMBL9716253 | 0.74 | PLA2G2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |