Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720754 | 0.89 | PDCD1 (0.42) | PDCD1CD274PDK2ALDH1A1MAPT | |
| SCHEMBL1443992 | 0.88 | PDCD1 (0.43) | PDCD1CD274PDK2ENPP1PRKAA2 | |
| SCHEMBL27555128 | 0.84 | TTR (0.43) | PDCD1CD274PDK2ALDH1A1L3MBTL1 | |
| SCHEMBL9720792 | 0.84 | PDCD1 (0.42) | PDCD1CD274PDK2ALDH1A1MAPT | |
| SCHEMBL9720735 | 0.84 | USP7 (0.34) | ALDH1A1MAPTL3MBTL1DHODHENPP1 | |
| SCHEMBL9720787 | 0.79 | ESR2 (0.42) | PDCD1CD274PDK2ENPP1CYP3A4 | |
| SCHEMBL1041243 | 0.79 | PDK2 (0.49) | PDCD1CD274PDK2SLC6A4SLC6A3 | |
| SCHEMBL9720784 | 0.77 | ESR2 (0.43) | PDCD1CD274PDK2ENPP1CYP3A4 | |
| SCHEMBL3858523 | 0.77 | KCNN4 (0.51) | PDCD1CD274PDK2ALDH1A1MAPT | |
| SCHEMBL13824010 | 0.75 | NR4A2 (0.48) | PDCD1CD274PDK2ENPP1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |