Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720735 | 0.87 | USP7 (0.34) | ALDH1A1MAPTL3MBTL1PTGS2PTGS1 | |
| SCHEMBL1443909 | 0.86 | ENPP1 (0.39) | ALDH1A1PTGS2PTGS1HTR2CMAPK14 | |
| SCHEMBL9720754 | 0.85 | PDCD1 (0.42) | ALDH1A1MAPTL3MBTL1PTGS2PTGS1 | |
| SCHEMBL9720743 | 0.84 | TAAR1 (0.36) | ALDH1A1MAPTL3MBTL1HIF1ADHODH | |
| SCHEMBL27487056 | 0.81 | TTR (0.39) | ALDH1A1L3MBTL1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL4429566 | 0.81 | PTGS2 (0.43) | ALDH1A1PTGS2PTGS1HTR2CMAPK14 | |
| SCHEMBL9720771 | 0.79 | TAAR1 (0.40) | DHODHADORA2AADORA1 | |
| Methylene Chloride SCHEMBL28982655 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1PTGS2PTGS1 | |
| SCHEMBL9720776 | 0.76 | TAAR1 (0.40) | DHODH | |
| SCHEMBL9720745 | 0.75 | DHODH (0.38) | ALDH1A1MAPTL3MBTL1HIF1ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | claimed |
| JP-2048569-A | — | — | None | — | — | JP | disclosed |
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| JP-H0248569-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1 HIMIDAZOLE | JOTA URIACH & CO SA | 1990-02-19 | — | — | JP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |