SCHEMBL9721920

SCHEMBL9721920

CCOC(=O)Nc1cccc(-c2ccc(NC(=O)O)cc2)c1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
MAPT P10636 1/20 0.62
MAPK1 P28482 1/20 0.62
HSD17B10 Q99714 1/20 0.62
MGLL Q99685 4/20 0.60
NPC1 O15118 1/20 0.56
HPGD P15428 1/20 0.56
CRHBP P24387 1/20 0.56
RAB9A P51151 1/20 0.56
CRHR2 Q13324 1/20 0.56
ALDH1A1 P00352 1/20 0.56
MTNR1B P49286 1/20 0.55
ENPP2 Q13822 1/20 0.55
ITGB3 P05106 1/20 0.53
ITGAV P06756 1/20 0.53
DHODH Q02127 1/20 0.52
CNR1 P21554 1/20 0.51
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565151 0.87 MAPK1 (0.79) LMNAMAPTMAPK1HSD17B10NPC1
SCHEMBL11079563 0.87 RAB9A (0.71) LMNAMAPTMAPK1HSD17B10NPC1
SCHEMBL5425007 0.86 NPC1 (0.55) LMNAMAPTMAPK1HSD17B10MGLL
SCHEMBL11038834 0.85 MAPK1 (0.58) LMNAMAPTMAPK1HSD17B10MGLL
SCHEMBL7565512 0.83 RAB9A (0.70) LMNAMAPTMAPK1HSD17B10NPC1
SCHEMBL11041108 0.83 MAPK1 (0.58) LMNAMAPTMAPK1HSD17B10MGLL
SCHEMBL5425003 0.83 NPC1 (0.52) LMNAMAPTMAPK1HSD17B10MGLL
SCHEMBL7565149 0.82 MAPK1 (0.81) LMNAMAPTMAPK1HSD17B10NPC1
SCHEMBL10790146 0.80 MAPT (0.61) LMNAMAPTMAPK1HSD17B10MGLL
Ethyl Phenylcarbamate SCHEMBL264865 0.80 RAB9A (0.75) LMNAMAPTMAPK1HSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010232-A1 Herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1980-04-30 EP claimed
US-5129950-A Modulation of membrane dependent metabolism A NATTERMANN & CIE GMBH (DE) 1992-07-14 US disclosed
EP-0250583-A1 USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS A. Nattermann & Cie. GmbH (DE) 1988-01-07 EP disclosed
EP-0231765-A1 Use of membrane modulators and products comprising such membrane modulators A. Nattermann & Cie. GmbH (DE) 1987-08-12 EP disclosed
WO-1987004048-A1 USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS A. NATTERMANN & CIE GMBH (DE) 1987-07-16 WO disclosed
EP-0068295-B1 A NEW HERBICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE A. Nattermann & Cie. GmbH (DE) 1985-08-28 EP disclosed
EP-0068295-A1 A new herbicidal composition, processes for its production and its use A. Nattermann & Cie. GmbH (DE) 1983-01-05 EP disclosed