Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721975 | 0.84 | LMNA (0.67) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9722139 | 0.81 | CYP2D6 (0.71) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL14587216 | 0.78 | CNR2 (0.53) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL1857833 | 0.76 | TSHR (0.39) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9722042 | 0.75 | ALDH1A1 (0.57) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL12203514 | 0.74 | HRH3 (0.61) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9313621 | 0.72 | CDK4 (0.51) | LMNAMAPTKMT2AMEN1HPGD | |
| SCHEMBL9722006 | 0.71 | CYP2D6 (0.67) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9722131 | 0.71 | CYP2D6 (0.56) | NR1I2LMNAADRA2ACYP2D6ACHE | |
| SCHEMBL9722145 | 0.70 | CYP2D6 (0.67) | NR1I2LMNAADRA2ACYP2D6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310122-B1 | ANTIFUNGAL COMPOSITION | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-24 | — | — | EP | claimed |
| EP-0310122-A1 | Antifungal composition | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | claimed |
| US-5120735-A | Synergistic mixture of miconazole, ketoconazole or fluconazole and N-4-tertbutylbenzyl-N-methyl-1-naphthalenemethylamine | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0310122-B1 | ANTIFUNGAL COMPOSITION | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |
| EP-0310122-A1 | Antifungal composition | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |