Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.51 |
| ▸ | CCND1 | P24385 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314839 | 0.78 | KMT2A (0.45) | MEN1KMT2AMLYCDNR1H4EPHX2 | |
| SCHEMBL6411595 | 0.77 | RIPK1 (0.42) | MEN1KMT2AATMMAPTRIPK1 | |
| SCHEMBL9721975 | 0.76 | LMNA (0.67) | MEN1KMT2ANR1H4EPHX2LMNA | |
| SCHEMBL21923501 | 0.76 | MLYCD (0.70) | MEN1KMT2AMLYCDNR1H4ESRRG | |
| SCHEMBL8059262 | 0.74 | PTGES (0.49) | CDK4CCND1MEN1KMT2AATM | |
| SCHEMBL9722175 | 0.72 | NR1I2 (0.47) | MEN1KMT2AHPGDTP53MAPT | |
| SCHEMBL9313576 | 0.72 | PDK1 (0.49) | CDK4CCND1MEN1KMT2AATM | |
| SCHEMBL4406602 | 0.70 | ESRRG (0.59) | CDK4CCND1MEN1KMT2ANR1H4 | |
| SCHEMBL29912623 | 0.69 | MEN1 (0.76) | MEN1KMT2AATMMLYCDRIPK1 | |
| SCHEMBL17874132 | 0.69 | MEN1 (0.76) | MEN1KMT2AATMMLYCDRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34770-E | 1-benzothiophene derivatives; side effect reduction | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5334628-A | Amine derivatives, processes for preparing the same and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| US-5200423-A | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5106866-A | Skin disorders | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5021458-A | Amine derivatives and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0164697-A2 | Amine derivatives, processes for preparing the same and fungicides containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-12-18 | — | — | EP | disclosed |