Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | HTR2A | P28223 | 7/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722262 | 0.88 | DRD2 (0.48) | DRD2HTR2AHTR1ADRD4SIGMAR1 | |
| SCHEMBL9722266 | 0.80 | HTR2A (0.49) | DRD2HTR2AHTR7HTR2CHTR1A | |
| SCHEMBL9722264 | 0.77 | DRD2 (0.50) | DRD2HTR2AHTR7HTR1AKCNH2 | |
| SCHEMBL9722260 | 0.77 | DRD2 (0.50) | DRD2HTR2AHTR7HTR1AKCNH2 | |
| SCHEMBL5996651 | 0.69 | ABCB11 (0.74) | DRD2HTR2AHTR2CHTR1AKCNH2 | |
| SCHEMBL5235646 | 0.67 | DRD2 (0.46) | DRD2DRD4DRD3MAPTKMT2A | |
| SCHEMBL9722378 | 0.67 | DRD2 (0.49) | DRD2HTR2AHTR1ADRD4SIGMAR1 | |
| SCHEMBL531012 | 0.67 | ACHE (0.52) | DRD2HTR2AHTR7HTR2CHTR1A | |
| SCHEMBL9681618 | 0.67 | HTR2A (0.48) | DRD2HTR2AHTR7HTR2CHTR1A | |
| SCHEMBL13448255 | 0.67 | HTR2A (0.60) | DRD2HTR2AHTR7HTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |