Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 10/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722378 | 0.87 | DRD2 (0.49) | HTR2ADRD2HTR1A | |
| SCHEMBL9187663 | 0.83 | HTR2A (0.53) | HTR2ADRD2HTR2CHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL9722317 | 0.82 | HTR2A (0.52) | HTR2ADRD2HTR2CHTR1AHTR7 | |
| SCHEMBL9722220 | 0.80 | DRD2 (0.43) | HTR2ADRD2HTR2CHTR1AHTR7 | |
| SCHEMBL9722237 | 0.76 | HTR2A (0.60) | HTR2ADRD2HTR2CHTR1AHTR7 | |
| SCHEMBL9722234 | 0.76 | HTR2A (0.60) | HTR2ADRD2HTR2CHTR1AHTR7 | |
| SCHEMBL13448255 | 0.74 | HTR2A (0.60) | HTR2ADRD2HTR1AHTR7KCNH2 | |
| SCHEMBL22302778 | 0.73 | DRD2 (0.63) | HTR2ADRD2HTR1AHTR7KCNH2 | |
| SCHEMBL9722226 | 0.72 | DRD2 (0.46) | HTR2ADRD2HTR2CHTR1AHTR7 | |
| SCHEMBL9190222 | 0.70 | HTR1A (0.50) | HTR2ADRD2HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |