Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872053 | 0.84 | TSHR (0.59) | TSHRTP53PRKCAALDH1A1TDP1 | |
| SCHEMBL28278024 | 0.82 | MEN1 (0.51) | TSHRTP53ALDH1A1TDP1KMT2A | |
| SCHEMBL3181495 | 0.80 | ALDH1A1 (0.61) | TSHRTP53PRKCAALDH1A1TDP1 | |
| SCHEMBL29964300 | 0.80 | ALDH1A1 (0.61) | TSHRTP53PRKCAALDH1A1TDP1 | |
| SCHEMBL5080030 | 0.78 | MEN1 (0.49) | TSHRTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL10062937 | 0.78 | TSHR (0.52) | TSHRTP53PRKCAALDH1A1TDP1 | |
| Ethylene SCHEMBL19616645 | 0.77 | ALDH1A1 (0.57) | TSHRTP53PRKCAALDH1A1TDP1 | |
| SCHEMBL3417176 | 0.77 | MEN1 (0.60) | TSHRTP53PRKCAALDH1A1TDP1 | |
| SCHEMBL17557410 | 0.76 | PRKCA (0.49) | TSHRTP53PRKCAALDH1A1TDP1 | |
| SCHEMBL5086221 | 0.76 | LMNA (0.47) | TSHRTP53PRKCAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122560-A | A curable polyesterurethane having a carboxy-containing diol as a monomer; automobile finishes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-16 | — | — | US | claimed |