Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24740670 | 0.81 | ADRA2C (0.38) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL17035510 | 0.81 | TAAR1 (0.37) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL9446725 | 0.76 | LMNA (0.36) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL15595870 | 0.75 | TAAR1 (0.36) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL9446846 | 0.73 | L3MBTL1 (0.40) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL17611046 | 0.69 | MAOB (0.40) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL24302612 | 0.69 | PDE2A (0.32) | NFKB1 | |
| Phenylethanolamine SCHEMBL7150657 | 0.68 | BLM (0.57) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| Phenylethanolamine SCHEMBL21723498 | 0.68 | BLM (0.57) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| Phenylethanolamine SCHEMBL296410 | 0.68 | BLM (0.57) | TAAR1NFKB1TSHRHIF1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106986-A | PREPARATION OF AMINOETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |