Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 12/20 | 0.73 |
| ▸ | PI4KA | P42356 | 12/20 | 0.73 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.73 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.71 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.71 |
| ▸ | PIP5K1C | O60331 | 4/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114470 | 1.00 | PIK3CA (0.73) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL5532470 | 0.89 | PIK3CA (0.82) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL29646253 | 0.89 | PIK3CA (0.82) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL16296381 | 0.86 | PIK3CA (0.77) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL77839 | 0.85 | RAB9A (0.61) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL25304004 | 0.85 | PIK3CA (0.66) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL31114629 | 0.85 | PIK3CA (0.66) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| SCHEMBL8773471 | 0.84 | PIK3CA (1.00) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| Hydrochloric Acid SCHEMBL10831817 | 0.84 | RAB9A (0.59) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG | |
| Hydrochloric Acid SCHEMBL27769376 | 0.84 | RAB9A (0.59) | PIK3CAPI4KAPI4KBPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INST NAT SANTE RECH MED (FR) | 2025-12-18 | — | — | US | disclosed |
| EP-4460500-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | BBOX1, NDUFB6, NDUFB5 | PIK3CA 3378/4885PI4KA 4333/4885PI4KB 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.