SCHEMBL9722766

SCHEMBL9722766

COC(=O)[C]1Cc2c(Cl)cccc2S1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.39
NR4A2 P43354 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC6A3 Q01959 1/20 0.37
NOTUM Q6P988 1/20 0.37
BCHE P06276 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
ALDH1A1 P00352 5/20 0.35
GAA P10253 5/20 0.35
KDM4E B2RXH2 3/20 0.35
GLA P06280 2/20 0.35
HPGD P15428 2/20 0.35
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28941926 0.70 HSD17B3 (0.42) MEN1KMT2ANOTUMBCHEALDH1A1
SCHEMBL517538 0.67 CA12 (0.61) POLBNR4A2MEN1KMT2ACA12
SCHEMBL5133394 0.65 HPGD (0.46) MEN1KMT2ABCHEALDH1A1KDM4E
SCHEMBL11436141 0.64 HPGD (0.45) MEN1KMT2ABCHEALDH1A1KDM4E
SCHEMBL9637150 0.64 CA12 (0.52) POLBNR4A2MEN1KMT2ASLC6A3
SCHEMBL11441135 0.64 HPGD (0.57) MEN1KMT2ABCHEALDH1A1KDM4E
SCHEMBL993113 0.63 TSHR (0.59) POLBNR4A2KMT2ASLC6A3ALDH1A1
SCHEMBL30488606 0.62 LMNA (0.61) POLBNR4A2MEN1KMT2ASLC6A3
SCHEMBL196555 0.62 LMNA (0.61) POLBNR4A2MEN1KMT2ASLC6A3
SCHEMBL8564502 0.61 CA12 (0.77) POLBNR4A2MEN1KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994563-A Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness CIBA-GEIGY CORPORATION (US) 1991-02-19 US claimed
EP-0349486-A2 Azo dyes, their preparation and their use CIBA-GEIGY AG (CH) 1990-01-03 EP claimed
US-5120872-A Textile dyeing CIBA-GEIGY CORPORATION (US) 1992-06-09 US disclosed
US-4994563-A Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness CIBA-GEIGY CORPORATION (US) 1991-02-19 US disclosed
EP-0349486-A2 Azo dyes, their preparation and their use CIBA-GEIGY AG (CH) 1990-01-03 EP disclosed