Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302032 | 0.85 | PDPK1 (0.59) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL9722793 | 0.83 | ALDH1A1 (0.57) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL28551546 | 0.83 | TTR (0.51) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL10797656 | 0.83 | ALDH1A1 (0.49) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL28136959 | 0.81 | PSMB8 (0.39) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL27872889 | 0.80 | PKLR (0.39) | ALDH1A1LMNASMN1; SMN2TTRPKLR | |
| SCHEMBL11341717 | 0.80 | TTR (0.35) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL9805781 | 0.80 | ALDH1A1 (0.49) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| Sulfuric Acid SCHEMBL9010159 | 0.79 | LMNA (0.81) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A | |
| Hydrochloric Acid SCHEMBL10910662 | 0.79 | ALDH1A1 (0.47) | PDPK1ALDH1A1LMNASMN1; SMN2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| EP-0048538-A1 | Azo dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | disclosed |
| US-4035350-A | Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |