Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324083 | 0.86 | POLB (0.48) | RAB9AHTTPOLBMAPTNPSR1 | |
| SCHEMBL4653234 | 0.73 | NPC1 (0.51) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL9856492 | 0.73 | SMN1; SMN2 (0.47) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL27993659 | 0.71 | TSHR (0.48) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL1538036 | 0.71 | KMT2A (0.69) | HTTPOLBTSHRMAPTGAA | |
| SCHEMBL11426475 | 0.71 | NPC1 (0.56) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL9633119 | 0.70 | ALDH1A1 (0.48) | HPGDALDH1A1SMN1; SMN2NPSR1GAA | |
| SCHEMBL11151614 | 0.70 | L3MBTL1 (0.50) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL11841476 | 0.70 | EPHX2 (0.50) | ALDH1A1SMN1; SMN2POLBTSHRMAPT | |
| SCHEMBL10827910 | 0.70 | MTNR1A (0.61) | NPC1RAB9AHPGDCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116826-A | SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |