Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947771 | 0.90 | GABRA1 (0.43) | EPHX2GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL8154668 | 0.83 | ESR2 (0.38) | EPHX2ACMSDCYP3A4CYP2C9 | |
| SCHEMBL2219914 | 0.82 | ACMSD (0.39) | EPHX2ACMSDNOS3NOS1NOS2 | |
| SCHEMBL9861573 | 0.82 | POLQ (0.38) | EPHX2ACMSDHDAC4HDAC2HDAC8 | |
| SCHEMBL11422572 | 0.81 | EPHX2 (0.47) | EPHX2ACMSDNOS3NOS1NOS2 | |
| SCHEMBL11161163 | 0.80 | ACMSD (0.57) | EPHX2ACMSDNOS3NOS1NOS2 | |
| SCHEMBL16850510 | 0.80 | ALDH1A1 (0.41) | EPHX2ACMSDNOS3NOS1NOS2 | |
| SCHEMBL3817408 | 0.80 | ESR2 (0.55) | CYP3A4CYP2C9 | |
| SCHEMBL4452694 | 0.80 | HDAC4 (0.38) | EPHX2ACMSDNOS3NOS1NOS2 | |
| SCHEMBL17029862 | 0.78 | EPHX2 (0.42) | EPHX2ACMSDNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180120701-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, MASK BLANK INCLUDING ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
| EP-0468162-A1 | Modified polyphenylene ether based thermoplastic moulding compositions | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |