Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.37 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219914 | 0.98 | ACMSD (0.39) | HDAC4HDAC2HDAC8ESR2ESR1 | |
| SCHEMBL12510597 | 0.82 | PTPN1 (0.39) | KDM4ECNR2 | |
| SCHEMBL9722928 | 0.80 | EPHX2 (0.47) | HDAC4HDAC2HDAC8ACMSDCYP3A4 | |
| SCHEMBL9999653 | 0.78 | ESR2 (0.37) | ESR2KDM4ECASP6 | |
| SCHEMBL27956345 | 0.77 | ACMSD (0.54) | HDAC4HDAC2HDAC8ESR2ESR1 | |
| SCHEMBL17029862 | 0.77 | EPHX2 (0.42) | HDAC4HDAC2HDAC8ACMSDEPHX2 | |
| SCHEMBL16850510 | 0.76 | ALDH1A1 (0.41) | HDAC4HDAC2HDAC8ESR2ESR1 | |
| SCHEMBL11629147 | 0.75 | KDM4E (0.38) | HDAC4HDAC2HDAC8ESR2ESR1 | |
| SCHEMBL9804552 | 0.74 | BCL2 (0.47) | CYP3A4 | |
| SCHEMBL778085 | 0.74 | HDAC8 (0.43) | HDAC4HDAC2HDAC8ESR2ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7586009-B2 | Bis-(hydroxybenzaldehyde) compound and novel polynuclear polyphenol compound derived therefrom and method for production thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20090076310-A1 | NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076310-A1 | NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF | DDT, PAH, HPD | HDAC4 400/4885HDAC2 503/4885HDAC8 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.