Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | ALPI | P09923 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581391 | 0.86 | ALDH1A1 (0.37) | ALDH1A1KDM5BALPLALPICA2 | |
| SCHEMBL9723104 | 0.84 | GABRA2 (0.37) | ALDH1A1HCAR1KDM5BLMNA | |
| SCHEMBL9723095 | 0.84 | HCAR1 (0.36) | ALDH1A1HCAR1KDM5BPOLB | |
| SCHEMBL9723051 | 0.80 | POLB (0.42) | ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL9343492 | 0.79 | KDM5B (0.38) | ALDH1A1HCAR1KDM5BLMNAPKM | |
| SCHEMBL9730652 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9723106 | 0.77 | GABRA2 (0.40) | KDM5BLMNA | |
| SCHEMBL9341586 | 0.77 | KDM5B (0.37) | ALDH1A1HCAR1KDM5BLMNAPKM | |
| SCHEMBL9593760 | 0.77 | GABRA2 (0.36) | ALDH1A1LMNAPOLB | |
| SCHEMBL9730727 | 0.74 | KDM5B (0.35) | ALDH1A1KDM5BALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104878-A | Insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | disclosed |