Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | ALPI | P09923 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581479 | 0.92 | ESR2 (0.32) | KDM5BESR2ALPLALPIELANE | |
| SCHEMBL9582173 | 0.91 | DDR1 (0.32) | KDM5BESR2ALPLALPI | |
| SCHEMBL9582286 | 0.91 | GABRA2 (0.38) | ALDH1A1GAAEIF4EBP1KDM4E | |
| SCHEMBL9730834 | 0.91 | ESR2 (0.33) | KDM5BESR2ELANEGAA | |
| SCHEMBL9581956 | 0.87 | TDP1 (0.38) | ALDH1A1GAAKDM4E | |
| SCHEMBL9732039 | 0.84 | ESR2 (0.31) | ESR2 | |
| SCHEMBL9730517 | 0.83 | DDR1 (0.31) | ESR2 | |
| SCHEMBL9582023 | 0.83 | GABRA2 (0.36) | ALDH1A1GAAEIF4EBP1KDM4E | |
| SCHEMBL9765847 | 0.83 | GAA (0.39) | KDM5BESR2ALPLALPIALDH1A1 | |
| SCHEMBL9581996 | 0.83 | HCAR1 (0.40) | ESR2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |