Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30485468 | 0.92 | L3MBTL1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2GAA | |
| SCHEMBL17578004 | 0.92 | L3MBTL1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2GAA | |
| SCHEMBL9723220 | 0.90 | L3MBTL1 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2GAA | |
| SCHEMBL9723167 | 0.89 | L3MBTL1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2GAA | |
| SCHEMBL10008733 | 0.89 | L3MBTL1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2GAA | |
| SCHEMBL2544586 | 0.87 | LMNA (0.49) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL12610716 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL19450271 | 0.83 | MAPT (0.48) | ALDH1A1HPGDHTTSMN1; SMN2GAA | |
| SCHEMBL10010397 | 0.81 | LMNA (0.44) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL18079242 | 0.81 | MAPT (0.47) | ALDH1A1HPGDHTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |