SCHEMBL9723233

SCHEMBL9723233

CCCC(CCC)(C(C)=O)C(=O)OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
PKM P14618 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 2/20 0.32
DGAT1 O75907 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
POLB P06746 1/20 0.32
PTPRB P23467 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL808737 0.88 MEN1 (0.38) ALDH1A1PKMMEN1KMT2ATHRB
SCHEMBL13606393 0.87 ATM (0.39) ALDH1A1PKMMEN1KMT2ATHRB
SCHEMBL18346585 0.86 ALDH1A1 (0.37) ALDH1A1PKMMEN1KMT2ATHRB
SCHEMBL4901424 0.83 ALDH1A1 (0.38) ALDH1A1PKMMEN1KMT2ATHRB
SCHEMBL16450968 0.83 MEN1 (0.39) MEN1KMT2A
SCHEMBL32679949 0.83 MAPT (0.38) MAPTPOLB
SCHEMBL28871790 0.82 PTPN1 (0.37) ALDH1A1MEN1KMT2AMAPTATM
SCHEMBL29067495 0.80 EPHX1 (0.36) ALDH1A1PKMMEN1KMT2ATHRB
SCHEMBL8053447 0.80 MEN1 (0.50) ALDH1A1PKMMEN1KMT2ATHRB
SCHEMBL17617155 0.79 ALDH1A1 (0.33) ALDH1A1PKMMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069561-B Preparation method of 2-ethyl valeric acid 湖南省湘中制药有限公司 2024-05-31 CN disclosed
CN-116947600-B Preparation method of 2-isopropyl valeric acid as valproic acid process impurity 湖南省湘中制药有限公司 2024-04-26 CN disclosed
CN-116874347-B Preparation method of impurity dipropylvaleric acid in valproic acid process 湖南省湘中制药有限公司 2024-03-29 CN disclosed
CN-117069561-A Preparation method of 2-ethyl valeric acid 湖南省湘中制药有限公司 2023-11-17 CN disclosed
CN-116947600-A Preparation method of 2-isopropyl valeric acid as valproic acid process impurity 湖南省湘中制药有限公司 2023-10-27 CN disclosed
CN-116874347-A Preparation method of impurity dipropylvaleric acid in valproic acid process 湖南省湘中制药有限公司 2023-10-13 CN disclosed
US-5101070-A From an acetoacetic acid ester; by-product minimization NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed