Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18346585 | 0.92 | ALDH1A1 (0.37) | MEN1KMT2ADGAT1ALDH1A1LMNA | |
| SCHEMBL29067495 | 0.91 | EPHX1 (0.36) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL28655390 | 0.89 | MEN1 (0.32) | MEN1KMT2ADGAT1ALDH1A1LMNA | |
| SCHEMBL29082258 | 0.89 | MEN1 (0.53) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL9723233 | 0.88 | ALDH1A1 (0.33) | MEN1KMT2ADGAT1ALDH1A1LMNA | |
| SCHEMBL28871790 | 0.88 | PTPN1 (0.37) | MEN1KMT2ADGAT1ALDH1A1LMNA | |
| SCHEMBL27908938 | 0.87 | MEN1 (0.39) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL15233853 | 0.85 | EPHX1 (0.39) | MEN1KMT2ADGAT1ALDH1A1LMNA | |
| SCHEMBL25200704 | 0.83 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTATM | |
| SCHEMBL28167346 | 0.83 | MMP8 (0.40) | LMNATSHRUSP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373737-A | Preparation, hydrolysis and application of dipropyldimethyl malonate | 湖南大学 | 2024-07-23 | — | — | CN | claimed |
| US-5344975-A | Process for production of lower alkanoic acids | WYCKOFF CHEMICAL COMPANY, INC. (US) | 1994-09-06 | — | — | US | claimed |
| US-12637680-B2 | Recombinant host cells for the production of malonate | LYGOS, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| CN-119709450-A | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119462378-A | Recovery and comprehensive utilization of dipropylmalonic monoester | 湖南大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-114616330-B | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118373737-A | Preparation, hydrolysis and application of dipropyldimethyl malonate | 湖南大学 | 2024-07-23 | — | — | CN | disclosed |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | LYGOS, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| CN-116768697-B | Method for preparing dipropylmalonic acid by using chloropropane as alkylating agent and application of dipropylmalonic acid | 湖南大学 | 2024-03-29 | — | — | CN | disclosed |
| WO-2024054828-A2 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | LYGOS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| CN-116023232-B | Preparation method of propyl malonic acid and homologs thereof | 湖南省湘中制药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20080076941-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ITAGAKI MAKOTO | 2008-03-27 | — | — | US | disclosed |
| US-20080076931-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ITAGAKI MAKOTO | 2008-03-27 | — | — | US | disclosed |
| US-7288674-B2 | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-30 | — | — | US | disclosed |
| US-20060149077-A1 | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
| EP-1593674-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-5344975-A | Process for production of lower alkanoic acids | WYCKOFF CHEMICAL COMPANY, INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0055797-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACETIC ACIDS AND/OR OF THEIR ESTERS AND OF SUBSTITUTED ACETONITRILES, RESPECTIVELY | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1985-05-29 | — | — | EP | disclosed |
| US-4417073-A | Process for the preparation of substituted acetic acids and derivatives thereof | DYNAMIT NOBEL A.G. (DE) | 1983-11-22 | — | — | US | disclosed |
| EP-0055797-A1 | Process for the preparation of substituted acetic acids and/or of their esters and of substituted acetonitriles, respectively | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149077-A1 | Optically active bisoxazoline compounds, process for production of the same and use thereof | ACSL3, ADSL, SQLE | MEN1 3119/4885KMT2A 4666/4885DGAT1 2839/4885 |
| US-20080076941-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ACSL3, ADSL, SQLE | MEN1 3119/4885KMT2A 4666/4885DGAT1 2839/4885 |
| US-20080076931-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF | ACSL3, ADSL, SQLE | MEN1 3119/4885KMT2A 4666/4885DGAT1 2839/4885 |
| US-12637680-B2 | Recombinant host cells for the production of malonate | DCXR, ETV1, LYPLA2 | MEN1 4165/4885KMT2A 361/4885DGAT1 387/4885 |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | ME1, MAL2, ME3 | MEN1 1464/4885KMT2A 4341/4885DGAT1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.