Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723922 | 0.78 | MAPT (0.43) | NPSR1MAPK1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9271491 | 0.75 | GABRA1 (0.69) | KMT2AALDH1A1HPGDGABRA1GABRB2 | |
| SCHEMBL9263567 | 0.72 | TP53 (0.45) | NPSR1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL1622004 | 0.72 | KDM4E (0.49) | CSF1RKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL9723941 | 0.71 | KMT2A (0.41) | NPSR1MAPK1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9271570 | 0.71 | GABRA1 (0.57) | ALDH1A1HPGDGABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL9272311 | 0.70 | KMT2A (0.42) | NPSR1MAPK1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9723934 | 0.70 | ALDH1A1 (0.52) | NPSR1KMT2ARXFP1ALDH1A1HPGD | |
| SCHEMBL13295306 | 0.67 | CSF1R (0.58) | CSF1RKMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL1061379 | 0.67 | KDM4E (0.64) | CSF1RKMT2ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |