Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724030 | 0.88 | POLB (0.36) | POLBKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL9387903 | 0.82 | MEN1 (0.35) | POLBKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL9727504 | 0.81 | FKBP1A (0.53) | POLBKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL8876637 | 0.79 | POLB (0.40) | POLBCACNA1ACACNA2D1CACNB1KMT2A | |
| SCHEMBL9724038 | 0.76 | KMT2A (0.39) | CACNA1ACACNA2D1CACNB1KMT2AMEN1 | |
| SCHEMBL8876139 | 0.76 | VHL (0.42) | POLBCACNA1ACACNA2D1CACNB1KMT2A | |
| SCHEMBL8876027 | 0.76 | POLB (0.36) | POLBCACNA1ACACNA2D1CACNB1KMT2A | |
| SCHEMBL13168009 | 0.76 | ALDH1A1 (0.45) | POLBKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL3606253 | 0.76 | ALDH1A1 (0.45) | POLBKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL8878158 | 0.75 | POLB (0.36) | POLBCACNA1ACACNA2D1CACNB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116836-A | Herbicides, insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |