SCHEMBL9724030

SCHEMBL9724030

CCOC(=O)C1CSCN1C(=O)Cc1c(C)cc(C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
HSD17B10 Q99714 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PREP P48147 1/20 0.35
ACE P12821 1/20 0.35
KMT2A Q03164 6/20 0.34
MEN1 O00255 5/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 2/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 2/20 0.34
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
P2RX7 Q99572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9724035 0.88 POLB (0.38) POLBHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL9724038 0.88 KMT2A (0.39) HSD17B10NPSR1PREPACEKMT2A
SCHEMBL9724044 0.85 P2RX7 (0.36) POLBHSD17B10NPSR1PREPACE
SCHEMBL9724032 0.83 KMT2A (0.38) POLBPREPACEKMT2AMEN1
SCHEMBL9724034 0.81 KMT2A (0.50) POLBHSD17B10PREPACEKMT2A
SCHEMBL9382534 0.81 MEN1 (0.32) POLBACEKMT2AMEN1ALDH1A1
SCHEMBL9724048 0.79 ALDH1A1 (0.40) POLBKMT2AMEN1ALDH1A1KDM4E
SCHEMBL8876139 0.78 VHL (0.42) POLBKMT2AMEN1ALDH1A1MAPK1
SCHEMBL8876027 0.78 POLB (0.36) POLBKMT2AMEN1ALDH1A1KDM4E
SCHEMBL9727504 0.78 FKBP1A (0.53) POLBHSD17B10KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5116836-A Herbicides, insecticides, miticides BAYER AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed