Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724113 | 0.88 | KDM4E (0.41) | ALOX5KDM4EPKML3MBTL1POLB | |
| SCHEMBL9724079 | 0.85 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9373997 | 0.84 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9724077 | 0.84 | ALOX5 (0.40) | ALOX5USP7 | |
| SCHEMBL9251943 | 0.82 | KDM4E (0.43) | ALOX5KDM4EL3MBTL1POLBSLC6A2 | |
| SCHEMBL9724081 | 0.78 | ALOX5 (0.43) | ALOX5KDM4EL3MBTL1 | |
| SCHEMBL9724097 | 0.74 | ALOX5 (0.41) | ALOX5PARP1 | |
| SCHEMBL9724100 | 0.74 | KDM4E (0.48) | KDM4EPKML3MBTL1POLBSLC6A2 | |
| SCHEMBL9724112 | 0.74 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9374059 | 0.72 | ALOX5 (0.46) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |