Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373997 | 0.86 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9724077 | 0.86 | ALOX5 (0.40) | ALOX5ICAM1SELE | |
| SCHEMBL9724082 | 0.85 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9724097 | 0.83 | ALOX5 (0.41) | ALOX5ICAM1SELE | |
| SCHEMBL9539694 | 0.82 | RAB9A (0.39) | ALOX5ICAM1SELEHTT | |
| SCHEMBL9724081 | 0.79 | ALOX5 (0.43) | ALOX5MAPTNPSR1 | |
| SCHEMBL28649609 | 0.78 | ICAM1 (0.39) | ICAM1SELEMAPTHTTSMN1; SMN2 | |
| SCHEMBL9373230 | 0.75 | ALDH1A1 (0.53) | ALOX5HTTSMN1; SMN2 | |
| SCHEMBL9538802 | 0.75 | RHEB (0.39) | ICAM1SELEMAPTHTTSMN1; SMN2 | |
| SCHEMBL9474486 | 0.74 | ALOX5 (0.46) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |