Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | LOX | P28300 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374053 | 0.85 | ALOX5 (0.61) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9724108 | 0.83 | ALOX5 (0.48) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9477371 | 0.76 | ALOX5 (0.65) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9724161 | 0.75 | KDM4E (0.46) | — | |
| SCHEMBL9724082 | 0.74 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9474923 | 0.73 | ALOX5 (0.61) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9724113 | 0.72 | KDM4E (0.41) | ALOX5 | |
| SCHEMBL9724133 | 0.71 | USP7 (0.60) | — | |
| SCHEMBL11392906 | 0.69 | HSD17B1 (0.52) | GAA | |
| SCHEMBL9474152 | 0.68 | ALOX5 (1.00) | ALOX5CYP1A2PTGESLMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |