Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724079 | 0.83 | ALOX5 (0.42) | ALOX5ICAM1SELE | |
| SCHEMBL9373997 | 0.83 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9724077 | 0.78 | ALOX5 (0.40) | ALOX5ICAM1SELE | |
| SCHEMBL9474486 | 0.74 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9724082 | 0.74 | ALOX5 (0.43) | ALOX5PARP1 | |
| SCHEMBL9724095 | 0.73 | TP53 (0.40) | PTGIRMMP2MMP9MMP12 | |
| SCHEMBL9475031 | 0.73 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9724081 | 0.71 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9374059 | 0.70 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL11398559 | 0.70 | PKM (0.53) | PTGIRICAM1SELECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |