Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586527 | 0.84 | RXRA (0.42) | RXRAKMOSTING1CYP26A1CYP3A4 | |
| SCHEMBL9586891 | 0.76 | KMT2A (0.47) | RXRATSHRKMT2ACYP26A1CYP3A4 | |
| SCHEMBL9724349 | 0.75 | KMT2A (0.46) | RXRATSHRKMT2ACYP26A1CYP3A4 | |
| SCHEMBL4407340 | 0.72 | RXRA (0.48) | RXRANPC1 | |
| SCHEMBL8922539 | 0.71 | TSHR (0.42) | TSHRKMOSTING1MEN1NPC1 | |
| SCHEMBL10842199 | 0.71 | GAA (0.47) | RXRATSHRMEN1KMT2ACYP26A1 | |
| SCHEMBL9588204 | 0.71 | RXRA (0.40) | RXRATSHRSTING1MEN1KMT2A | |
| SCHEMBL9185753 | 0.70 | CYP3A4 (0.50) | RXRAMEN1NPC1KMT2ACYP26A1 | |
| SCHEMBL3693703 | 0.70 | TSHR (0.78) | TSHRMEN1NPC1KMT2ACYP3A4 | |
| SCHEMBL8522801 | 0.70 | RXRA (0.60) | RXRACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286523-B1 | AROMATIC DERIVATIVES OF BUTYRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR COSMETIC AND PHARMACEUTICAL USE | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |