Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993582 | 0.78 | KMT2A (0.50) | SMN1; SMN2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9724366 | 0.73 | PARP1 (0.39) | SMN1; SMN2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL8596365 | 0.71 | MEN1 (0.57) | SMN1; SMN2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL10790420 | 0.68 | KMT2A (0.41) | SMN1; SMN2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL6205636 | 0.68 | NR4A2 (0.65) | PRSS1CTSGCTRB1CMA1SMN1; SMN2 | |
| SCHEMBL6754862 | 0.67 | MAPK1 (0.46) | PRSS1CTSGCTRB1CMA1SMN1; SMN2 | |
| SCHEMBL11276739 | 0.66 | NR4A2 (0.58) | SMN1; SMN2MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL3252460 | 0.66 | KMT2A (0.70) | PRSS1CTSGCTRB1CMA1SMN1; SMN2 | |
| SCHEMBL5655365 | 0.65 | PRSS1 (0.68) | PRSS1CTSGCTRB1CMA1SMN1; SMN2 | |
| SCHEMBL2257751 | 0.65 | TSHR (0.44) | PRSS1CTSGCTRB1CMA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162505-A | Proteins modified with positively charged carriers and compositions prepared therefrom | CENTOCOR (US) | 1992-11-10 | — | — | US | disclosed |