Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371252 | 0.79 | GAA (0.46) | SMN1; SMN2CYP3A4KDM4EHPGDKMT2A | |
| SCHEMBL9724362 | 0.78 | PARP1 (0.36) | PARP1SMN1; SMN2CYP3A4KDM4EMEN1 | |
| SCHEMBL9724338 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP3A4KDM4EMEN1MAPT | |
| SCHEMBL6993582 | 0.77 | KMT2A (0.50) | SMN1; SMN2CYP3A4KDM4EMEN1MAPT | |
| SCHEMBL8597576 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2MEN1MAPTKMT2ATDP1 | |
| SCHEMBL31418693 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2MAPK1ALDH1A1HTT | |
| SCHEMBL30442090 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2MAPK1ALDH1A1HTT | |
| SCHEMBL5352301 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2MAPK1ALDH1A1HTT | |
| SCHEMBL10975765 | 0.74 | KMT2A (0.40) | SMN1; SMN2MAPTMAPK1KMT2ATDP1 | |
| SCHEMBL22043005 | 0.74 | HDAC2 (0.45) | SMN1; SMN2KDM4EMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162505-A | Proteins modified with positively charged carriers and compositions prepared therefrom | CENTOCOR (US) | 1992-11-10 | — | — | US | disclosed |