Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485667 | 0.79 | SLC7A5 (0.40) | KMT2AALOX15MAPK1MGLLALDH1A1 | |
| SCHEMBL9724366 | 0.77 | PARP1 (0.39) | SMN1; SMN2KMT2AMEN1CYP3A4HPGD | |
| SCHEMBL13997654 | 0.77 | NR4A2 (0.49) | SMN1; SMN2KMT2AMEN1HPGDMAPT | |
| SCHEMBL133554 | 0.75 | KMT2A (0.53) | SMN1; SMN2KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL19309377 | 0.75 | KMT2A (0.53) | SMN1; SMN2KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL10720603 | 0.75 | L3MBTL1 (0.50) | SMN1; SMN2KMT2AMAPTTDP1RAB9A | |
| SCHEMBL25763807 | 0.74 | ALDH1A1 (0.66) | SMN1; SMN2KMT2AMEN1CYP3A4HPGD | |
| SCHEMBL142707 | 0.74 | MGAM (0.31) | MAPTMGLLALDH1A1 | |
| SCHEMBL11194320 | 0.72 | KMT2A (0.50) | SMN1; SMN2KMT2AMEN1HPGDMAPT | |
| SCHEMBL9211733 | 0.72 | KMT2A (0.47) | SMN1; SMN2KMT2AMEN1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162505-A | Proteins modified with positively charged carriers and compositions prepared therefrom | CENTOCOR (US) | 1992-11-10 | — | — | US | disclosed |
| US-5144043-A | Coupling protein or peptide to radionucleotide; labeling antibodies | CENTOCOR (US) | 1992-09-01 | — | — | US | disclosed |