Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416619 | 0.95 | APP (0.56) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6366353 | 0.92 | NPC1 (0.59) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2390980 | 0.90 | LMNA (0.54) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL29066085 | 0.88 | MTNR1A (0.62) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5881099 | 0.88 | APP (0.73) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3782064 | 0.86 | LMNA (0.55) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL8607887 | 0.86 | ALDH1A1 (0.49) | APPNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL1114985 | 0.85 | NPC1 (0.63) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL31011346 | 0.85 | NPC1 (0.63) | APPNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6281909 | 0.85 | CYP1A2 (0.64) | NPC1HPGDMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336259-A1 | PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF | FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC (CA) | 2014-11-13 | — | — | US | disclosed |
| WO-2012167364-A1 | PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF | FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) | 2012-12-13 | — | — | WO | disclosed |
| CN-1129604-C | Amino acid derivatives and their use as thrombin inhibitors | ASTRA AB (SE) | 2003-12-03 | — | — | CN | disclosed |
| CN-1226895-A | Amino acid derivatives and their use as thrombin inhibitors | ASTRA AB (SE) | 1999-08-25 | — | — | CN | disclosed |
| US-5158948-A | Treating neurological and psychological disorders | ABBOTT LABORATORIES (US) | 1992-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336259-A1 | PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF | GPX1, CAT, GPX4 | APP 1978/4885NPC1 2108/4885RAB9A 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.