SCHEMBL9724437

SCHEMBL9724437

Cc1cnc2[c]c(Cl)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
CYP1A2 P05177 3/20 0.40
KDM4E B2RXH2 1/20 0.36
PSMD14 O00487 1/20 0.36
COPS5 Q92905 1/20 0.36
CYP2A6 P11509 2/20 0.33
PARP1 P09874 1/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7875010 0.81 NOS1 (0.33) CYP2A6NOS1
SCHEMBL2889003 0.68 CYP1A2 (0.50) CCR1CCR5CCR8CYP1A2KDM4E
SCHEMBL9381631 0.67 LMNA (0.43) CCR1CCR5CCR8CYP1A2KDM4E
SCHEMBL18207370 0.67 CYP1A2 (0.48) CYP1A2KDM4ECYP2A6
SCHEMBL30492603 0.66 CCR1 (1.00) CCR1CCR5CCR8CYP1A2KDM4E
SCHEMBL686948 0.66 CCR1 (1.00) CCR1CCR5CCR8CYP1A2KDM4E
SCHEMBL27635367 0.65 CCR1 (0.52) CCR1CCR5CCR8CYP1A2KDM4E
SCHEMBL435765 0.65 CYP1A2 (0.57) CCR1CCR5CCR8CYP1A2KDM4E
SCHEMBL11826319 0.64 CYP2A6 (0.44) CYP1A2KDM4ECYP2A6
SCHEMBL10838838 0.64 CCR1 (0.67) CCR1CCR5CCR8CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5123952-A Postemergence herbicides BASF AKTIENGESELLSCHAFT (DE) 1992-06-23 US disclosed