Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724796 | 0.83 | HDAC1 (0.52) | RAB9ANPC1L3MBTL1POLB | |
| SCHEMBL9724971 | 0.83 | KCNQ2 (0.54) | GAAMEN1KMT2ARAB9AMAPT | |
| SCHEMBL9724808 | 0.80 | MEN1 (0.53) | GAAMEN1KMT2ARAB9AMAPT | |
| SCHEMBL9724825 | 0.80 | TSHR (0.55) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL9724964 | 0.79 | MME (0.58) | MEN1KMT2AMAPTHPGD | |
| SCHEMBL9724829 | 0.78 | BACE1 (0.54) | GAAMEN1KMT2ARAB9AMAPT | |
| SCHEMBL16993945 | 0.76 | CTSL (0.59) | RAB9ANPC1L3MBTL1 | |
| SCHEMBL9724970 | 0.75 | MAPT (0.55) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL9724978 | 0.74 | KMT2A (0.52) | GAAMEN1KMT2ARAB9AMAPT | |
| SCHEMBL9724833 | 0.74 | LMNA (0.54) | MEN1KMT2ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |