Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724959 | 0.83 | GAA (0.55) | NPC1RAB9AL3MBTL1POLB | |
| SCHEMBL9724971 | 0.82 | KCNQ2 (0.54) | MAPK1NPC1RAB9APOLB | |
| SCHEMBL9724871 | 0.79 | MME (0.57) | MAPK1 | |
| SCHEMBL9724808 | 0.79 | MEN1 (0.53) | MAPK1NPC1RAB9APOLB | |
| SCHEMBL9724923 | 0.79 | RAB9A (0.50) | HDAC1MAPK1NPC1RAB9A | |
| SCHEMBL9724825 | 0.78 | TSHR (0.55) | NPC1RAB9A | |
| SCHEMBL9724786 | 0.75 | DDX3X (0.51) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL9724829 | 0.74 | BACE1 (0.54) | MAPK1NPC1RAB9A | |
| SCHEMBL9724978 | 0.73 | KMT2A (0.52) | NPC1RAB9A | |
| SCHEMBL9724833 | 0.73 | LMNA (0.54) | NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |