Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.43 |
| ▸ | GRK6 | P43250 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740661 | 0.88 | TSHR (0.56) | TSHRCYP3A4KDM4EALDH1A1KAT2B | |
| SCHEMBL9725392 | 0.81 | MAPT (0.46) | TSHRCYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL6013576 | 0.81 | ALDH1A1 (0.43) | TSHRKDM4EALDH1A1KAT2BHCAR3 | |
| SCHEMBL22942130 | 0.73 | KMT2A (0.41) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9725444 | 0.73 | PIK3CD (0.47) | KDM4EALDH1A1KAT2BHCAR3MAPT | |
| SCHEMBL22510151 | 0.72 | ALDH1A1 (0.45) | CYP3A4KDM4EALDH1A1GAAHCAR3 | |
| SCHEMBL9725432 | 0.72 | SMN1; SMN2 (0.61) | KDM4EALDH1A1GAAHCAR3MAPT | |
| SCHEMBL3314688 | 0.71 | LMNA (0.42) | ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL4764057 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAHCAR3MAPT | |
| SCHEMBL26119562 | 0.71 | AKR1B1 (0.55) | TSHRCYP3A4KDM4EALDH1A1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |