Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725783 | 0.94 | CAPN1 (0.48) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL7268421 | 0.82 | CAPN1 (0.52) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL7270180 | 0.77 | CTSL (0.51) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL7269500 | 0.77 | CTSL (0.50) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL7275321 | 0.76 | CAPN1 (0.51) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL7268416 | 0.76 | CAPN1 (0.58) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL7268180 | 0.75 | TACR1 (0.64) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL30819309 | 0.74 | CTSL (0.65) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL9725809 | 0.73 | ALDH1A1 (0.48) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL17959489 | 0.73 | CAPN1 (0.72) | CTSLCAPN1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |