Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293627 | 0.87 | ALDH1A1 (0.58) | ALDH1A1ALOX15CAPN1CTSLCTSK | |
| SCHEMBL9725783 | 0.78 | CAPN1 (0.48) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL7293543 | 0.78 | ALDH1A1 (0.61) | ALDH1A1ALOX15CTSLCTSKCTSB | |
| SCHEMBL7269500 | 0.77 | CTSL (0.50) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL7270180 | 0.74 | CTSL (0.51) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL9725799 | 0.73 | CTSL (0.48) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL7269259 | 0.73 | EPHX1 (0.47) | ALDH1A1 | |
| SCHEMBL7287953 | 0.71 | KDM4E (0.40) | ALDH1A1ALOX15CTSLCTSKCTSB | |
| SCHEMBL764062 | 0.71 | CTSL (0.68) | ALDH1A1ALOX15CTSLCTSKCTSB | |
| SCHEMBL10250520 | 0.71 | CTSL (0.68) | ALDH1A1ALOX15CTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |