Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 10/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725799 | 0.94 | CTSL (0.48) | CAPN1CTSLCTSBRENHTRA1 | |
| SCHEMBL7270180 | 0.83 | CTSL (0.51) | CAPN1CTSLCTSBRENHTRA1 | |
| SCHEMBL7269500 | 0.83 | CTSL (0.50) | CAPN1CTSLCTSBHTRA1CTSK | |
| SCHEMBL7269191 | 0.79 | CTSL (0.61) | CAPN1CTSLCTSBCTSKCTSS | |
| SCHEMBL9725809 | 0.78 | ALDH1A1 (0.48) | CAPN1CTSLCTSBCTSKCTSS | |
| SCHEMBL7268421 | 0.78 | CAPN1 (0.52) | CAPN1CTSLCTSBRENHTRA1 | |
| SCHEMBL7269496 | 0.78 | CTSL (0.52) | CAPN1CTSLCTSBRENHTRA1 | |
| SCHEMBL9725792 | 0.77 | CAPN1 (0.56) | CAPN1CTSLCTSBRENHTRA1 | |
| SCHEMBL7270176 | 0.77 | CAPN1 (0.56) | CAPN1CTSLCTSBRENHTRA1 | |
| SCHEMBL7275321 | 0.76 | CAPN1 (0.51) | CAPN1CTSLCTSBRENHTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |